MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells

Reprogramming of mitochondria metabolism occurs during naïve to primed pluripotency differentiation in mouse embryonic stem cells (ESCs). Here the authors show that mitochondrial MTCH2 regulates mitochondrial fusion and that this fusion is required for naïve to primed pluripotency conversion

Guardado en:

Detalles Bibliográficos
Autores principales:	Amir Bahat, Andres Goldman, Yehudit Zaltsman, Dilshad H. Khan, Coral Halperin, Emmanuel Amzallag, Vladislav Krupalnik, Michael Mullokandov, Alon Silberman, Ayelet Erez, Aaron D. Schimmer, Jacob H. Hanna, Atan Gross
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3b42662e2cea47e7be6870e3d559ad27
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:3b42662e2cea47e7be6870e3d559ad27
record_format	dspace
spelling	oai:doaj.org-article:3b42662e2cea47e7be6870e3d559ad272021-12-02T14:39:46ZMTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells10.1038/s41467-018-07519-w2041-1723https://doaj.org/article/3b42662e2cea47e7be6870e3d559ad272018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07519-whttps://doaj.org/toc/2041-1723Reprogramming of mitochondria metabolism occurs during naïve to primed pluripotency differentiation in mouse embryonic stem cells (ESCs). Here the authors show that mitochondrial MTCH2 regulates mitochondrial fusion and that this fusion is required for naïve to primed pluripotency conversionAmir BahatAndres GoldmanYehudit ZaltsmanDilshad H. KhanCoral HalperinEmmanuel AmzallagVladislav KrupalnikMichael MullokandovAlon SilbermanAyelet ErezAaron D. SchimmerJacob H. HannaAtan GrossNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Amir Bahat Andres Goldman Yehudit Zaltsman Dilshad H. Khan Coral Halperin Emmanuel Amzallag Vladislav Krupalnik Michael Mullokandov Alon Silberman Ayelet Erez Aaron D. Schimmer Jacob H. Hanna Atan Gross MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells
description	Reprogramming of mitochondria metabolism occurs during naïve to primed pluripotency differentiation in mouse embryonic stem cells (ESCs). Here the authors show that mitochondrial MTCH2 regulates mitochondrial fusion and that this fusion is required for naïve to primed pluripotency conversion
format	article
author	Amir Bahat Andres Goldman Yehudit Zaltsman Dilshad H. Khan Coral Halperin Emmanuel Amzallag Vladislav Krupalnik Michael Mullokandov Alon Silberman Ayelet Erez Aaron D. Schimmer Jacob H. Hanna Atan Gross
author_facet	Amir Bahat Andres Goldman Yehudit Zaltsman Dilshad H. Khan Coral Halperin Emmanuel Amzallag Vladislav Krupalnik Michael Mullokandov Alon Silberman Ayelet Erez Aaron D. Schimmer Jacob H. Hanna Atan Gross
author_sort	Amir Bahat
title	MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells
title_short	MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells
title_full	MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells
title_fullStr	MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells
title_full_unstemmed	MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells
title_sort	mtch2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/3b42662e2cea47e7be6870e3d559ad27
work_keys_str_mv	AT amirbahat mtch2mediatedmitochondrialfusiondrivesexitfromnaivepluripotencyinembryonicstemcells AT andresgoldman mtch2mediatedmitochondrialfusiondrivesexitfromnaivepluripotencyinembryonicstemcells AT yehuditzaltsman mtch2mediatedmitochondrialfusiondrivesexitfromnaivepluripotencyinembryonicstemcells AT dilshadhkhan mtch2mediatedmitochondrialfusiondrivesexitfromnaivepluripotencyinembryonicstemcells AT coralhalperin mtch2mediatedmitochondrialfusiondrivesexitfromnaivepluripotencyinembryonicstemcells AT emmanuelamzallag mtch2mediatedmitochondrialfusiondrivesexitfromnaivepluripotencyinembryonicstemcells AT vladislavkrupalnik mtch2mediatedmitochondrialfusiondrivesexitfromnaivepluripotencyinembryonicstemcells AT michaelmullokandov mtch2mediatedmitochondrialfusiondrivesexitfromnaivepluripotencyinembryonicstemcells AT alonsilberman mtch2mediatedmitochondrialfusiondrivesexitfromnaivepluripotencyinembryonicstemcells AT ayeleterez mtch2mediatedmitochondrialfusiondrivesexitfromnaivepluripotencyinembryonicstemcells AT aarondschimmer mtch2mediatedmitochondrialfusiondrivesexitfromnaivepluripotencyinembryonicstemcells AT jacobhhanna mtch2mediatedmitochondrialfusiondrivesexitfromnaivepluripotencyinembryonicstemcells AT atangross mtch2mediatedmitochondrialfusiondrivesexitfromnaivepluripotencyinembryonicstemcells
_version_	1718390525945446400

MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells

Ejemplares similares