Lipid vesicles containing transferrin receptor binding peptide TfR-T12 and octa-arginine conjugate stearyl-R8 efficiently treat brain glioma along with glioma stem cells

Abstract Surgery and radiotherapy cannot fully remove brain glioma; thus, chemotherapy continues to play an important role in treatment of this illness. However, because of the restriction of the blood-brain barrier (BBB) and the regeneration of glioma stem cells, post-chemotherapy relapse usually o...

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Autores principales: Li-Min Mu, Ying-Zi Bu, Lei Liu, Hong-Jun Xie, Rui-Jun Ju, Jia-Shuan Wu, Fan Zeng, Yao Zhao, Jing-Ying Zhang, Wan-Liang Lu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/3b4ad1d8fd21474e988947e08319834e
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