Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy
When examining the evolution of treatment resistance in breast cancer, perceived genomic changes may be due to clonal evolution or heterogeneous tumors. Here, the authors show that apparent clonal change can in fact be due to pre-treatment heterogeneity, and samples from at least two regions are nec...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2019
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/3b5c30a996d54c2086cfff5a285a1014 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|