Energy landscape underlying spontaneous insertion and folding of an alpha-helical transmembrane protein into a bilayer
The detailed folding mechanisms of membrane proteins in their natural bilayer-like environments remains poorly understood due to the lack of tools for measuring stabilities and kinetics. Here, by simulating the folding of GlpG in a bilayer, the authors provide support for the helical-hairpin hypothe...
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Autores principales: | Wei Lu, Nicholas P. Schafer, Peter G. Wolynes |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/3b629c330a4c40749ac3167daefde321 |
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