Platelet Phenotype Analysis of COVID-19 Patients Reveals Progressive Changes in the Activation of Integrin αIIbβ3, F13A1, the SARS-CoV-2 Target EIF4A1 and Annexin A5

Platelet Phenotype Analysis of COVID-19 Patients Reveals Progressive Changes in the Activation of Integrin αIIbβ3, F13A1, the SARS-CoV-2 Target EIF4A1 and Annexin A5

Background: The fatal consequences of an infection with severe acute respiratory syndrome coronavirus 2 are not only caused by severe pneumonia, but also by thrombosis. Platelets are important regulators of thrombosis, but their involvement in the pathogenesis of COVID-19 is largely unknown. The aim...

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Auteurs principaux: Huriye Ercan, Waltraud Cornelia Schrottmaier, Anita Pirabe, Anna Schmuckenschlager, David Pereyra, Jonas Santol, Erich Pawelka, Marianna T. Traugott, Christian Schörgenhofer, Tamara Seitz, Mario Karolyi, Jae-Won Yang, Bernd Jilma, Alexander Zoufaly, Alice Assinger, Maria Zellner
Format: article
Langue:EN
Publié: Frontiers Media S.A. 2021
Sujets:
COVID-19
thrombosis
platelets
integrin αIIbβ3
coagulation factor XIII (FXIII, F13A1)
antiphospholipid syndrome
Diseases of the circulatory (Cardiovascular) system
RC666-701
Accès en ligne:https://doaj.org/article/3b745cc794fd43db9f5982030c9086d2
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https://doaj.org/article/3b745cc794fd43db9f5982030c9086d2

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