Exploring the link between germline and somatic genetic alterations in breast carcinogenesis.

Recent genome-wide association studies (GWASs) have identified candidate genes contributing to cancer risk through low-penetrance mutations. Many of these genes were unexpected and, intriguingly, included well-known players in carcinogenesis at the somatic level. To assess the hypothesis of a germli...

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Auteurs principaux: Núria Bonifaci, Bohdan Górski, Bartlomiej Masojć, Dominika Wokołorczyk, Anna Jakubowska, Tadeusz Dębniak, Antoni Berenguer, Jordi Serra Musach, Joan Brunet, Joaquín Dopazo, Steven A Narod, Jan Lubiński, Conxi Lázaro, Cezary Cybulski, Miguel Angel Pujana
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2010
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Accès en ligne:https://doaj.org/article/3b8960dabb5348e1918a4064e9b2dc72
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