Measurement of hindered diffusion in complex geometries for high-speed studies of single-molecule forces

Abstract In a high-speed single-molecule experiment with a force probe, a protein is tethered between two substrates that are manipulated to exert force on the system. To avoid nonspecific interactions between the protein and nearby substrates, the protein is usually attached to the substrates throu...

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Autores principales: Tobias F. Bartsch, Camila M. Villasante, Felicitas E. Hengel, Ahmed Touré, Daniel M. Firester, Aaron Oswald, A. J. Hudspeth
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/3b89f7a1c30345afaf37ac9fb427dc85
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