Serotonin signaling modulates aging-associated metabolic network integrity in response to nutrient choice in Drosophila melanogaster

Lyu et al analysed metabolic network integrity in Drosophila melanogaster to assess the systemic effects of nutrient choice. By knocking out the serotonin receptor, 5-HT2A, they demonstrated that the effects of different macronutrients on the stability of metabolic networks is mediated through serot...

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Auteurs principaux: Yang Lyu, Daniel E. L. Promislow, Scott D. Pletcher
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/3b8e0c67b3c546be951870d33a33d1f7
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Résumé:Lyu et al analysed metabolic network integrity in Drosophila melanogaster to assess the systemic effects of nutrient choice. By knocking out the serotonin receptor, 5-HT2A, they demonstrated that the effects of different macronutrients on the stability of metabolic networks is mediated through serotonin signalling.