Lateral inhibition by Martinotti interneurons is facilitated by cholinergic inputs in human and mouse neocortex
Parvalbumin and somatostatin expressing interneurons mediate lateral inhibition between cortical neurons. Here the authors report the mechanisms by which acetylcholine from the basal forebrain selectively augments lateral inhibition via Martinotti cells and show that this is conserved in humans.
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Auteurs principaux: | Joshua Obermayer, Tim S. Heistek, Amber Kerkhofs, Natalia A. Goriounova, Tim Kroon, Johannes C. Baayen, Sander Idema, Guilherme Testa-Silva, Jonathan J. Couey, Huibert D. Mansvelder |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
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Sujets: | |
Accès en ligne: | https://doaj.org/article/3bb32f558e4e41c8984accb0680d2e97 |
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