The geometry of clinical labs and wellness states from deeply phenotyped humans
Longitudinal multi-omics measurements are highly valuable in studying heterogeneity in health and disease phenotypes. Here, the authors apply Pareto Task Inference to analyze the clinical lab tests of 3094 individuals and find three wellness states, and one aberrant health state defining this cohort...
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Nature Portfolio
2021
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oai:doaj.org-article:3bc217cadb6347bdb67f294b25377a9c2021-12-02T18:06:34ZThe geometry of clinical labs and wellness states from deeply phenotyped humans10.1038/s41467-021-23849-82041-1723https://doaj.org/article/3bc217cadb6347bdb67f294b25377a9c2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23849-8https://doaj.org/toc/2041-1723Longitudinal multi-omics measurements are highly valuable in studying heterogeneity in health and disease phenotypes. Here, the authors apply Pareto Task Inference to analyze the clinical lab tests of 3094 individuals and find three wellness states, and one aberrant health state defining this cohort.Anat ZimmerYael KoremNoa RappaportTomasz WilmanskiPriyanka BaloniKathleen JadeMax RobinsonAndrew T. MagisJennifer LovejoySean M. GibbonsLeroy HoodNathan D. PriceNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021) |
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Science Q Anat Zimmer Yael Korem Noa Rappaport Tomasz Wilmanski Priyanka Baloni Kathleen Jade Max Robinson Andrew T. Magis Jennifer Lovejoy Sean M. Gibbons Leroy Hood Nathan D. Price The geometry of clinical labs and wellness states from deeply phenotyped humans |
description |
Longitudinal multi-omics measurements are highly valuable in studying heterogeneity in health and disease phenotypes. Here, the authors apply Pareto Task Inference to analyze the clinical lab tests of 3094 individuals and find three wellness states, and one aberrant health state defining this cohort. |
format |
article |
author |
Anat Zimmer Yael Korem Noa Rappaport Tomasz Wilmanski Priyanka Baloni Kathleen Jade Max Robinson Andrew T. Magis Jennifer Lovejoy Sean M. Gibbons Leroy Hood Nathan D. Price |
author_facet |
Anat Zimmer Yael Korem Noa Rappaport Tomasz Wilmanski Priyanka Baloni Kathleen Jade Max Robinson Andrew T. Magis Jennifer Lovejoy Sean M. Gibbons Leroy Hood Nathan D. Price |
author_sort |
Anat Zimmer |
title |
The geometry of clinical labs and wellness states from deeply phenotyped humans |
title_short |
The geometry of clinical labs and wellness states from deeply phenotyped humans |
title_full |
The geometry of clinical labs and wellness states from deeply phenotyped humans |
title_fullStr |
The geometry of clinical labs and wellness states from deeply phenotyped humans |
title_full_unstemmed |
The geometry of clinical labs and wellness states from deeply phenotyped humans |
title_sort |
geometry of clinical labs and wellness states from deeply phenotyped humans |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/3bc217cadb6347bdb67f294b25377a9c |
work_keys_str_mv |
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