Ephrin-B3 coordinates timed axon targeting and amygdala spinogenesis for innate fear behaviour

The molecular mechanism underlying initial circuit wiring in amygdala is poorly understood. Here the authors show that ephrin-B3 is required for axon targeting and amygdala spinogenesis during a critical period in development, and plays an important role in amygdala mediated fear responses.

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Autores principales: Xiao-Na Zhu, Xian-Dong Liu, Suya Sun, Hanyi Zhuang, Jing-Yu Yang, Mark Henkemeyer, Nan-Jie Xu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/3bdc6f1b81b242618699efb4dbc31bc1
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