Ephrin-B3 coordinates timed axon targeting and amygdala spinogenesis for innate fear behaviour

The molecular mechanism underlying initial circuit wiring in amygdala is poorly understood. Here the authors show that ephrin-B3 is required for axon targeting and amygdala spinogenesis during a critical period in development, and plays an important role in amygdala mediated fear responses.

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Autores principales:	Xiao-Na Zhu, Xian-Dong Liu, Suya Sun, Hanyi Zhuang, Jing-Yu Yang, Mark Henkemeyer, Nan-Jie Xu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3bdc6f1b81b242618699efb4dbc31bc1
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spelling	oai:doaj.org-article:3bdc6f1b81b242618699efb4dbc31bc12021-12-02T14:39:48ZEphrin-B3 coordinates timed axon targeting and amygdala spinogenesis for innate fear behaviour10.1038/ncomms110962041-1723https://doaj.org/article/3bdc6f1b81b242618699efb4dbc31bc12016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms11096https://doaj.org/toc/2041-1723The molecular mechanism underlying initial circuit wiring in amygdala is poorly understood. Here the authors show that ephrin-B3 is required for axon targeting and amygdala spinogenesis during a critical period in development, and plays an important role in amygdala mediated fear responses.Xiao-Na ZhuXian-Dong LiuSuya SunHanyi ZhuangJing-Yu YangMark HenkemeyerNan-Jie XuNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xiao-Na Zhu Xian-Dong Liu Suya Sun Hanyi Zhuang Jing-Yu Yang Mark Henkemeyer Nan-Jie Xu Ephrin-B3 coordinates timed axon targeting and amygdala spinogenesis for innate fear behaviour
description	The molecular mechanism underlying initial circuit wiring in amygdala is poorly understood. Here the authors show that ephrin-B3 is required for axon targeting and amygdala spinogenesis during a critical period in development, and plays an important role in amygdala mediated fear responses.
format	article
author	Xiao-Na Zhu Xian-Dong Liu Suya Sun Hanyi Zhuang Jing-Yu Yang Mark Henkemeyer Nan-Jie Xu
author_facet	Xiao-Na Zhu Xian-Dong Liu Suya Sun Hanyi Zhuang Jing-Yu Yang Mark Henkemeyer Nan-Jie Xu
author_sort	Xiao-Na Zhu
title	Ephrin-B3 coordinates timed axon targeting and amygdala spinogenesis for innate fear behaviour
title_short	Ephrin-B3 coordinates timed axon targeting and amygdala spinogenesis for innate fear behaviour
title_full	Ephrin-B3 coordinates timed axon targeting and amygdala spinogenesis for innate fear behaviour
title_fullStr	Ephrin-B3 coordinates timed axon targeting and amygdala spinogenesis for innate fear behaviour
title_full_unstemmed	Ephrin-B3 coordinates timed axon targeting and amygdala spinogenesis for innate fear behaviour
title_sort	ephrin-b3 coordinates timed axon targeting and amygdala spinogenesis for innate fear behaviour
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/3bdc6f1b81b242618699efb4dbc31bc1
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Ephrin-B3 coordinates timed axon targeting and amygdala spinogenesis for innate fear behaviour

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