Transcriptional responses of skeletal stem/progenitor cells to hindlimb unloading and recovery correlate with localized but not systemic multi-systems impacts

Abstract Disuse osteoporosis (DO) results from mechanical unloading of weight-bearing bones and causes structural changes that compromise skeletal integrity, leading to increased fracture risk. Although bone loss in DO results from imbalances in osteoblast vs. osteoclast activity, its effects on ske...

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Autores principales: Cori N. Booker, Christopher L. Haga, Siddaraju V. Boregowda, Jacqueline Strivelli, Donald G. Phinney
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/3c13a6b3b57648d89fc2e9a8526667c9
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