Asymmetric benzylic C(sp3)−H acylation via dual nickel and photoredox catalysis

Chiral α-aryl ketones are versatile building blocks, and represent important pharmacophores existing in many drug molecules such as ibuprofen and naproxen. Here the authors for such ketones but using nickel and photoredox dual catalysis in asymmetric benzylic C−H acylation of alkylarenes and employi...

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Autores principales: Leitao Huan, Xiaomin Shu, Weisai Zu, De Zhong, Haohua Huo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/3c17fee165d643adbb5f5970a04f1828
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