Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88

Abstract Autophagy, the processes of delivery of intracellular components to lysosomes, regulates induction of inflammation. Inducible macroautophagy degrades inflammasomes and dysfunctional mitochondria to downregulate inflammatory signals. Nonetheless, the effects of constitutive basal autophagy o...

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Autores principales: Takeshi Into, Toshi Horie, Megumi Inomata, Jin Gohda, Jun-ichiro Inoue, Yukitaka Murakami, Shumpei Niida
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/3c1b7fc1246b49098a73e79887c60ae9
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