Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88
Abstract Autophagy, the processes of delivery of intracellular components to lysosomes, regulates induction of inflammation. Inducible macroautophagy degrades inflammasomes and dysfunctional mitochondria to downregulate inflammatory signals. Nonetheless, the effects of constitutive basal autophagy o...
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Main Authors: | Takeshi Into, Toshi Horie, Megumi Inomata, Jin Gohda, Jun-ichiro Inoue, Yukitaka Murakami, Shumpei Niida |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
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Online Access: | https://doaj.org/article/3c1b7fc1246b49098a73e79887c60ae9 |
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