Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88
Abstract Autophagy, the processes of delivery of intracellular components to lysosomes, regulates induction of inflammation. Inducible macroautophagy degrades inflammasomes and dysfunctional mitochondria to downregulate inflammatory signals. Nonetheless, the effects of constitutive basal autophagy o...
Enregistré dans:
Auteurs principaux: | Takeshi Into, Toshi Horie, Megumi Inomata, Jin Gohda, Jun-ichiro Inoue, Yukitaka Murakami, Shumpei Niida |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/3c1b7fc1246b49098a73e79887c60ae9 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Identification and function of myeloid differentiation factor 88 (MyD88) in Litopenaeus vannamei.
par: Shuang Zhang, et autres
Publié: (2012) -
Lipopolysaccharide-induced NF-κB nuclear translocation is primarily dependent on MyD88, but TNFα expression requires TRIF and MyD88
par: Jiro Sakai, et autres
Publié: (2017) -
MyD88 promotes myoblast fusion in a cell-autonomous manner
par: Sajedah M. Hindi, et autres
Publié: (2017) -
MyD88 in Macrophages Enhances Liver Fibrosis by Activation of NLRP3 Inflammasome in HSCs
par: Shuang Ge, et autres
Publié: (2021) -
MyD88 is a critical regulator of hematopoietic cell-mediated neuroprotection seen after stroke.
par: Catherine E Downes, et autres
Publié: (2013)