Combining physicochemical and evolutionary information for protein contact prediction.

We introduce a novel contact prediction method that achieves high prediction accuracy by combining evolutionary and physicochemical information about native contacts. We obtain evolutionary information from multiple-sequence alignments and physicochemical information from predicted ab initio protein...

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Bibliographic Details
Main Authors: Michael Schneider, Oliver Brock
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
R
Q
Online Access:https://doaj.org/article/3c4d836df80648e082cc76f0502da619
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