From reaction kinetics to dementia: A simple dimer model of Alzheimer's disease etiology.

Oligomers of the amyloid β-protein (Aβ) have been implicated in the pathogenesis of Alzheimer's disease (AD) through their toxicity towards neurons. Understanding the process of oligomerization may contribute to the development of therapeutic agents, but this has been difficult due to the compl...

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Auteurs principaux: Michael R Lindstrom, Manuel B Chavez, Elijah A Gross-Sable, Eric Y Hayden, David B Teplow
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2021
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Accès en ligne:https://doaj.org/article/3c582736fd1d498ab466555361aee08a
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