Deletion of the Zinc Transporter Lipoprotein AdcAII Causes Hyperencapsulation of <named-content content-type="genus-species">Streptococcus pneumoniae</named-content> Associated with Distinct Alleles of the Type I Restriction-Modification System

ABSTRACT The capsule is the dominant Streptococcus pneumoniae virulence factor, yet how variation in capsule thickness is regulated is poorly understood. Here, we describe an unexpected relationship between mutation of adcAII, which encodes a zinc uptake lipoprotein, and capsule thickness. Partial d...

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Auteurs principaux: Claire Durmort, Giuseppe Ercoli, Elisa Ramos-Sevillano, Suneeta Chimalapati, Richard D. Haigh, Megan De Ste Croix, Katherine Gould, Jason Hinds, Yann Guerardel, Thierry Vernet, Marco Oggioni, Jeremy S. Brown
Format: article
Langue:EN
Publié: American Society for Microbiology 2020
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Accès en ligne:https://doaj.org/article/3c6b97acfd444f4693bf02410dff2bee
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