Deletion of the Zinc Transporter Lipoprotein AdcAII Causes Hyperencapsulation of <named-content content-type="genus-species">Streptococcus pneumoniae</named-content> Associated with Distinct Alleles of the Type I Restriction-Modification System

Deletion of the Zinc Transporter Lipoprotein AdcAII Causes Hyperencapsulation of <named-content content-type="genus-species">Streptococcus pneumoniae</named-content> Associated with Distinct Alleles of the Type I Restriction-Modification System

ABSTRACT The capsule is the dominant Streptococcus pneumoniae virulence factor, yet how variation in capsule thickness is regulated is poorly understood. Here, we describe an unexpected relationship between mutation of adcAII, which encodes a zinc uptake lipoprotein, and capsule thickness. Partial d...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Claire Durmort, Giuseppe Ercoli, Elisa Ramos-Sevillano, Suneeta Chimalapati, Richard D. Haigh, Megan De Ste Croix, Katherine Gould, Jason Hinds, Yann Guerardel, Thierry Vernet, Marco Oggioni, Jeremy S. Brown
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
Streptococcus pneumoniae
capsule expression
virulence
AdcAII
restriction modification
SpnD39III
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/3c6b97acfd444f4693bf02410dff2bee
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares