Toll-like receptor-4 null mutation causes fetal loss and fetal growth restriction associated with impaired maternal immune tolerance in mice
Abstract Maternal immune adaptation to accommodate pregnancy depends on sufficient availability of regulatory T (Treg) cells to enable embryo implantation. Toll-like receptor 4 is implicated as a key upstream driver of a controlled inflammatory response, elicited by signals in male partner seminal f...
Enregistré dans:
Auteurs principaux: | Hon Y. Chan, Lachlan M. Moldenhauer, Holly M. Groome, John E. Schjenken, Sarah A. Robertson |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/3c743f6abbc646929af7155a782242ef |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Paired maternal and fetal metabolomics reveal a differential fingerprint in preeclampsia versus fetal growth restriction
par: Lina Youssef, et autres
Publié: (2021) -
Listeria monocytogenes cytoplasmic entry induces fetal wastage by disrupting maternal Foxp3+ regulatory T cell-sustained fetal tolerance.
par: Jared H Rowe, et autres
Publié: (2012) -
Fetal and maternal medicine review
Publié: (1992) -
Sexually dimorphic patterns in maternal circulating microRNAs in pregnancies complicated by fetal growth restriction
par: Bernadette C. Baker, et autres
Publié: (2021) -
Fetal growth restriction impairs hippocampal neurogenesis and cognition via Tet1 in offspring
par: Wen Chen, et autres
Publié: (2021)