Two-step synthesis of chiral fused tricyclic scaffolds from phenols via desymmetrization on nickel
Tricyclic furanic compounds with multiple chiral centers are found in a variety of natural products. Here, the authors show a highly enantioselective nickel-catalyzed procedure to access tricyclic oxygen-containing scaffolds with five contiguous chiral centers.
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Main Authors: | Ravindra Kumar, Yoichi Hoshimoto, Eri Tamai, Masato Ohashi, Sensuke Ogoshi |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
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Subjects: | |
Online Access: | https://doaj.org/article/3c787649d39c4ad8b5b8b89e6d424d32 |
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