7,8-Dihydroxyflavone improves neuropathological changes in the brain of Tg26 mice, a model for HIV-associated neurocognitive disorder

Abstract The combined antiretroviral therapy era has significantly increased the lifespan of people with HIV (PWH), turning a fatal disease to a chronic one. However, this lower but persistent level of HIV infection increases the susceptibility of HIV-associated neurocognitive disorder (HAND). There...

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Main Authors: Joseph Bryant, Sanketh Andhavarapu, Christopher Bever, Poornachander Guda, Akhil Katuri, Udit Gupta, Muhammed Arvas, Girma Asemu, Alonso Heredia, Volodymyr Gerzanich, Marc J. Simard, Tapas Kumar Makar
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/3cf4056459194055aa7956f2a4e46b58
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