A study of the mechanism of the chaperone-like function of an scFv of human creatine kinase by computer simulation.

A new application of antibodies is to use them as macromolecular chaperones. Protein antigens usually have multiple epitopes, thus, there may be a plurality of antibodies binding to one antigen. However, not all antibodies that bind to one antigen could act as a chaperone. Experiments show that some...

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Bibliographic Details
Main Authors: Jianyu Feng, Hong Guo, Sen Li, Tun Lu
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
R
Q
Online Access:https://doaj.org/article/3cf5c2bd4793473aaf370a78c12b2d79
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