A study of the mechanism of the chaperone-like function of an scFv of human creatine kinase by computer simulation.
A new application of antibodies is to use them as macromolecular chaperones. Protein antigens usually have multiple epitopes, thus, there may be a plurality of antibodies binding to one antigen. However, not all antibodies that bind to one antigen could act as a chaperone. Experiments show that some...
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Main Authors: | Jianyu Feng, Hong Guo, Sen Li, Tun Lu |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2013
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Subjects: | |
Online Access: | https://doaj.org/article/3cf5c2bd4793473aaf370a78c12b2d79 |
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