Basement membrane collagen IV deficiency promotes abdominal aortic aneurysm formation

Abstract Abdominal aortic aneurysm (AAA) is a complex disease which is incompletely accounted for. Basement membrane (BM) Collagen IV (COL4A1/A2) is abundant in the artery wall, and several lines of evidence indicate a protective role of baseline COL4A1/A2 in AAA development. Using Col4a1/a2 hemizyg...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: L. B. Steffensen, J. Stubbe, J. S. Lindholt, H. C. Beck, M. Overgaard, M. Bloksgaard, F. Genovese, S. Holm Nielsen, M. L. T. Tha, S. K. Bang-Moeller, M. K. T. Hong Lin, J. H. Larsen, D. R. Hansen, G. T. Jones, M. J. Bown, M. A. Karsdal, L. M. Rasmussen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
R
Q
Acceso en línea:https://doaj.org/article/3d1b5c247947475dacbe108ba6ec5da2
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!