Mining the transcriptome for rare disease therapies: a comparison of the efficiencies of two data mining approaches and a targeted cell-based drug screen

Rare diseases: drug re-discovery Canadian researchers use three different approaches to identify drugs that could be repurposed to treat rare genetic diseases. Prompted by the growing gap between known rare diseases and therapies and postulating that diseases might be treated with drugs that modulat...

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Détails bibliographiques
Auteurs principaux: A. J. Mears, S. C. Schock, J. Hadwen, S. Putos, D. Dyment, K. M. Boycott, Alex MacKenzie
Format: article
Langue:EN
Publié: Nature Portfolio 2017
Sujets:
R
Accès en ligne:https://doaj.org/article/3d2784f19fee4e1ebd89fab035bb9d11
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