Molecular Basis of the Versatile Regulatory Mechanism of HtrA-Type Protease AlgW from Pseudomonas aeruginosa

Molecular Basis of the Versatile Regulatory Mechanism of HtrA-Type Protease AlgW from Pseudomonas aeruginosa

HtrA-family proteases are commonly employed to sense the protein folding stress and activate the regulated intramembrane proteolysis (RIP) cascade in Gram-negative bacteria. Here, we reveal the unique dual-signal activation and dynamic regulation properties of AlgW, an HtrA-type protease triggerin...

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Main Authors: Tao Li, Yingjie Song, Liming Luo, Ninglin Zhao, Lihui He, Mei Kang, Changcheng Li, Yibo Zhu, Yalin Shen, Chang Zhao, Jing Yang, Qin Huang, Xingyu Mou, Zhiyong Zong, Jinliang Yang, Hong Tang, Yongxing He, Rui Bao
Format: article
Language:EN
Published: American Society for Microbiology 2021
Subjects:
Microbiology
QR1-502
Online Access:https://doaj.org/article/3d364595942a4765b601a32837d729aa
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https://doaj.org/article/3d364595942a4765b601a32837d729aa

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