4-methylumbelliferone-mediated polarization of M1 macrophages correlate with decreased hepatocellular carcinoma aggressiveness in mice

4-methylumbelliferone-mediated polarization of M1 macrophages correlate with decreased hepatocellular carcinoma aggressiveness in mice

Abstract Hepatocellular carcinoma (HCC) arises in the setting of advanced liver fibrosis, a dynamic and complex inflammatory disease. The tumor microenvironment (TME) is a mixture of cellular components including cancer cells, cancer stem cells (CSCs), tumor-associated macrophages (TAM), and dendrit...

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Autores principales: Marcelo M. Rodríguez, Agostina Onorato, María José Cantero, Luciana Domínguez, Juan Bayo, Esteban Fiore, Mariana García, Catalina Atorrasagasti, Ali Canbay, Mariana Malvicini, Guillermo D. Mazzolini
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/3d3c6f33ea01415b96af9f1753a19b1c
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