4-methylumbelliferone-mediated polarization of M1 macrophages correlate with decreased hepatocellular carcinoma aggressiveness in mice
Abstract Hepatocellular carcinoma (HCC) arises in the setting of advanced liver fibrosis, a dynamic and complex inflammatory disease. The tumor microenvironment (TME) is a mixture of cellular components including cancer cells, cancer stem cells (CSCs), tumor-associated macrophages (TAM), and dendrit...
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Main Authors: | Marcelo M. Rodríguez, Agostina Onorato, María José Cantero, Luciana Domínguez, Juan Bayo, Esteban Fiore, Mariana García, Catalina Atorrasagasti, Ali Canbay, Mariana Malvicini, Guillermo D. Mazzolini |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/3d3c6f33ea01415b96af9f1753a19b1c |
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