The Innate Immune Response to Herpes Simplex Virus 1 Infection Is Dampened in the Newborn Brain and Can Be Modulated by Exogenous Interferon Beta To Improve Survival
ABSTRACT Newborns are particularly susceptible to severe forms of herpes simplex virus 1 (HSV-1) infection, including encephalitis and multisystemic disseminated disease. The underlying age-dependent differences in the immune response that explain this increased susceptibility relative to the adult...
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Main Authors: | Daniel Giraldo, Douglas R. Wilcox, Richard Longnecker |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2020
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Online Access: | https://doaj.org/article/3d7d2a01e2804a8ebb0db9f5befec314 |
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