The Innate Immune Response to Herpes Simplex Virus 1 Infection Is Dampened in the Newborn Brain and Can Be Modulated by Exogenous Interferon Beta To Improve Survival

ABSTRACT Newborns are particularly susceptible to severe forms of herpes simplex virus 1 (HSV-1) infection, including encephalitis and multisystemic disseminated disease. The underlying age-dependent differences in the immune response that explain this increased susceptibility relative to the adult...

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Bibliographic Details
Main Authors: Daniel Giraldo, Douglas R. Wilcox, Richard Longnecker
Format: article
Language:EN
Published: American Society for Microbiology 2020
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Online Access:https://doaj.org/article/3d7d2a01e2804a8ebb0db9f5befec314
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