GCN2 has inhibitory effect on human immunodeficiency virus-1 protein synthesis and is cleaved upon viral infection.

The reversible phosphorylation of the alpha-subunit of eukaryotic translation initiation factor 2 (eIF2alpha) is a well-characterized mechanism of translational control in response to a wide variety of cellular stresses, including viral infection. Beside PKR, the eIF2alpha kinase GCN2 participates i...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Javier del Pino, José Luis Jiménez, Iván Ventoso, Alfredo Castelló, Ma Ángeles Muñoz-Fernández, César de Haro, Juan José Berlanga
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
R
Q
Acceso en línea:https://doaj.org/article/3dad714f473849a4a52310c241437ed1
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!