Involvement of MAP3K8 and miR-17-5p in poor virologic response to interferon-based combination therapy for chronic hepatitis C.

Despite advances in chronic hepatitis C treatment, a proportion of patients respond poorly to treatment. This study aimed to explore hepatic mRNA and microRNA signatures involved in hepatitis C treatment resistance. Global hepatic mRNA and microRNA expression profiles were compared using microarray...

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Auteurs principaux:	Akihito Tsubota, Kaoru Mogushi, Hideki Aizaki, Ken Miyaguchi, Keisuke Nagatsuma, Hiroshi Matsudaira, Tatsuya Kushida, Tomomi Furihata, Hiroshi Tanaka, Tomokazu Matsuura
Format:	article
Langue:	EN
Publié:	Public Library of Science (PLoS) 2014
Sujets:	Medicine R Science Q
Accès en ligne:	https://doaj.org/article/3db261d955cf4f138548473a638d8423
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