Transcriptional profiling of human microglia reveals grey–white matter heterogeneity and multiple sclerosis-associated changes

It is unclear if early pathological changes in normal-appearing multiple sclerosis (MS) tissue are reflected by molecular changes in microglia, which might contribute to lesion initiation. Here, authors demonstrate significant intrinsic differences in the human microglial transcriptome between grey...

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Main Authors: Marlijn van der Poel, Thomas Ulas, Mark R. Mizee, Cheng-Chih Hsiao, Suzanne S. M. Miedema, Adelia, Karianne G. Schuurman, Boy Helder, Sander W. Tas, Joachim L. Schultze, Jörg Hamann, Inge Huitinga
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/3dba4ae06f6a4f6d8d2e10b0073b7819
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