Dynamics of lineage commitment revealed by single-cell transcriptomics of differentiating embryonic stem cells

Commitment to different fates by differentiating pluripotent cells depends upon integration of external and internal signals. Here the authors analyse the entry of mouse embryonic stem cells into retinoic acid-mediated differentiation using single cell transcriptomics with high temporal resolution.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Stefan Semrau, Johanna E. Goldmann, Magali Soumillon, Tarjei S. Mikkelsen, Rudolf Jaenisch, Alexander van Oudenaarden
Format: article
Langue:EN
Publié: Nature Portfolio 2017
Sujets:
Q
Accès en ligne:https://doaj.org/article/3dd6ae9a564b472e9b62d001d23e4414
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!