Improving the alignment quality of consistency based aligners with an evaluation function using synonymous protein words.

Most sequence alignment tools can successfully align protein sequences with higher levels of sequence identity. The accuracy of corresponding structure alignment, however, decreases rapidly when considering distantly related sequences (<20% identity). In this range of identity, alignments optimiz...

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Autores principales: Hsin-Nan Lin, Cédric Notredame, Jia-Ming Chang, Ting-Yi Sung, Wen-Lian Hsu
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/3e287cb4b2ed49a38fb4e64e13092cce
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