YAP and TAZ are transcriptional co-activators of AP-1 proteins and STAT3 during breast cellular transformation

The YAP and TAZ paralogs are transcriptional co-activators recruited to target sites by TEAD proteins. Here, we show that YAP and TAZ are also recruited by JUNB (a member of the AP-1 family) and STAT3, key transcription factors that mediate an epigenetic switch linking inflammation to cellular trans...

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Autores principales: Lizhi He, Henry Pratt, Mingshi Gao, Fengxiang Wei, Zhiping Weng, Kevin Struhl
Formato: article
Lenguaje:EN
Publicado: eLife Sciences Publications Ltd 2021
Materias:
YAP
TAZ
R
Q
Acceso en línea:https://doaj.org/article/3e3ffdd2b83944b3af6bdbc7d2c096f9
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