YAP and TAZ are transcriptional co-activators of AP-1 proteins and STAT3 during breast cellular transformation
The YAP and TAZ paralogs are transcriptional co-activators recruited to target sites by TEAD proteins. Here, we show that YAP and TAZ are also recruited by JUNB (a member of the AP-1 family) and STAT3, key transcription factors that mediate an epigenetic switch linking inflammation to cellular trans...
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Auteurs principaux: | Lizhi He, Henry Pratt, Mingshi Gao, Fengxiang Wei, Zhiping Weng, Kevin Struhl |
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Format: | article |
Langue: | EN |
Publié: |
eLife Sciences Publications Ltd
2021
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Accès en ligne: | https://doaj.org/article/3e3ffdd2b83944b3af6bdbc7d2c096f9 |
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