Oligonucleotide conjugated multi-functional adeno-associated viruses

Abstract Recombinant adeno-associated viruses (AAVs) are among the most commonly used vehicles for in vivo gene delivery. However, their tropism is limited, and additionally their efficacy can be negatively affected by prevalence of neutralizing antibodies in sera. Methodologies to systematically en...

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Autores principales: Dhruva Katrekar, Ana M. Moreno, Genghao Chen, Atharv Worlikar, Prashant Mali
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/3e63cac820274427a3c7a71f9e4eb6ba
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