Chronic BDNF simultaneously inhibits and unmasks superficial dorsal horn neuronal activity

Abstract Brain-derived neurotrophic factor (BDNF) is critically involved in the pathophysiology of chronic pain. However, the mechanisms of BDNF action on specific neuronal populations in the spinal superficial dorsal horn (SDH) requires further study. We used chronic BDNF treatment (200 ng/ml, 5–6 ...

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Auteurs principaux: Sascha R. A. Alles, Max A. Odem, Van B. Lu, Ryan M. Cassidy, Peter A. Smith
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/3e69283edd694e9888f90e726ca6e55a
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