New Investigations with Lupane Type A-Ring Azepane Triterpenoids for Antimycobacterial Drug Candidate Design

New Investigations with Lupane Type A-Ring Azepane Triterpenoids for Antimycobacterial Drug Candidate Design

Twenty lupane type A-ring azepano-triterpenoids were synthesized from betulin and its related derivatives and their antitubercular activity against <i>Mycobacterium tuberculosis</i>, mono-resistant MTB strains, and nontuberculous strains <i>Mycobacterium abscessus</i> and Myc...

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Autores principales: Oxana Kazakova, Roxana Racoviceanu, Anastasiya Petrova, Marius Mioc, Adrian Militaru, Lucreția Udrescu, Mihai Udrescu, Adrian Voicu, Jason Cummings, Gregory Robertson, Diane J. Ordway, Richard A. Slayden, Codruța Șoica
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
triterpenoids
lupane
betulin
azepane
<i>M. tuberculosis</i>
resistant MTB strains
Biology (General)
QH301-705.5
Chemistry
QD1-999
Acceso en línea:https://doaj.org/article/3e7403c52ff547d18f5dcf6d20eacf42
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https://doaj.org/article/3e7403c52ff547d18f5dcf6d20eacf42

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