Investigation of brain tissue infiltration by medulloblastoma cells in an ex vivo model

Abstract Medulloblastoma (MB) is a paediatric cancer of the cerebellum that can develop cerebellar and leptomeningeal metastases. Local brain tissue infiltration, the underlying cause of metastasis and relapse, remains unexplored. We developed a novel approach to investigate tissue infiltration of M...

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Autores principales: Anuja Neve, Karthiga Santhana Kumar, Dimitra Tripolitsioti, Michael A. Grotzer, Martin Baumgartner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/3e8243d7dce1495abdc67618cc837a72
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