Glycan chip based on structure-switchable DNA linker for on-chip biosynthesis of cancer-associated complex glycans

Current methods for on-chip glycan biosynthesis suffer from analysing products, often resulting in poor purity and yield. Here the authors report a glycan chip developed by introducing a pH-responsive i-motif DNA linker to control the immobilization and isolation of glycans on chips.

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Auteurs principaux: Hye Ryoung Heo, Kye Il Joo, Jeong Hyun Seo, Chang Sup Kim, Hyung Joon Cha
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/3eb2ecbd5a8b4c19b5c913abf739dbae
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