Glycan chip based on structure-switchable DNA linker for on-chip biosynthesis of cancer-associated complex glycans
Current methods for on-chip glycan biosynthesis suffer from analysing products, often resulting in poor purity and yield. Here the authors report a glycan chip developed by introducing a pH-responsive i-motif DNA linker to control the immobilization and isolation of glycans on chips.
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Auteurs principaux: | Hye Ryoung Heo, Kye Il Joo, Jeong Hyun Seo, Chang Sup Kim, Hyung Joon Cha |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/3eb2ecbd5a8b4c19b5c913abf739dbae |
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