Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination

Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination

Adverse life events have been associated with reduced survival in cancer patients. Here, the authors explore the mechanism responsible and show that chronic stress in mice activates a signalling cascade in macrophages and tumour cells, which results in restructuring of the tumour lymphatic system, p...

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Autores principales: Caroline P. Le, Cameron J. Nowell, Corina Kim-Fuchs, Edoardo Botteri, Jonathan G. Hiller, Hilmy Ismail, Matthew A. Pimentel, Ming G. Chai, Tara Karnezis, Nicole Rotmensz, Giuseppe Renne, Sara Gandini, Colin W. Pouton, Davide Ferrari, Andreas Möller, Steven A. Stacker, Erica K. Sloan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/3eb5ab2a6c134a019c85df9430bef9cf
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https://doaj.org/article/3eb5ab2a6c134a019c85df9430bef9cf

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