Chaperone biomarkers of lifespan and penetrance track the dosages of many other proteins
In C. elegans the chaperone hsp-16.2 predicts the penetrance of mutations and lifespan after heat shock, but it is not known why cells express different amounts of hsp-16.2. Here the authors show hsp-16.2 tracks differences in global gene expression capacity, rather than differences in signaling or...
Guardado en:
Autores principales: | Nikolay Burnaevskiy, Bryan Sands, Soo Yun, Patricia M. Tedesco, Thomas E. Johnson, Matt Kaeberlein, Roger Brent, Alexander Mendenhall |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/3eca43d27d3a4ec0ac746c9204fa7760 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice
por: Kan Xie, et al.
Publicado: (2017) -
Introns control stochastic allele expression bias
por: Bryan Sands, et al.
Publicado: (2021) -
A prion accelerates proliferation at the expense of lifespan
por: David M Garcia, et al.
Publicado: (2021) -
Evolution of natural lifespan variation and molecular strategies of extended lifespan in yeast
por: Alaattin Kaya, et al.
Publicado: (2021) -
Many lives, many masters
por: Weiss, Brian