Towards the generation of B-cell receptor retrogenic mice.

Transgenic expression of B- and T-cell receptors (BCRs and TCRs, respectively) has been a standard tool to study lymphocyte development and function in vivo. The generation of transgenic mice is time-consuming and, therefore, a faster method to study the biology of defined lymphocyte receptors in vi...

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Auteurs principaux: Jenny Freitag, Sylvia Heink, Edith Roth, Jürgen Wittmann, Hans-Martin Jäck, Thomas Kamradt
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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Accès en ligne:https://doaj.org/article/3ee9a7f3c7684310a73784dbc8fd9ae3
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