TRIB1 is a positive regulator of hepatocyte nuclear factor 4-alpha

Abstract The TRIB1 locus has been linked to both cardiovascular disease and hepatic steatosis. Recent efforts have revealed TRIB1 to be a major regulator of liver function, largely, but not exclusively, via CEBPA degradation. We recently uncovered a functional interaction between TRIB1 and HNF4A, an...

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Autores principales: Sébastien Soubeyrand, Amy Martinuk, Ruth McPherson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/3ef6b6c9fa4342a49ea9bf015bfea87b
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